Nicotine Antagonists

15 rows  · Nicotinic antagonist. A nicotinic antagonist is a type of anticholinergic drug that inhibits the action of acetylcholine (ACh) at nicotinic acetylcholine receptors. These compounds are mainly used for peripheral muscle paralysis in surgery, the classical agent of this type being tubocurarine, but some centrally acting compounds such as bupropion,…

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It should be noted that when administered peripherally, several bis-quaternary ammonium antagonists, including bPiDDB, specifically decreased nicotine self-administration and reinstatement of nicotine seeking in rats, providing proof of concept of this representative class of drug as a new pharmacotherapy for nicotine addiction.

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Nicotinic antagonists discriminate between the ganglionic (neuronal, NN) and the neuromuscular nicotinic AChR (NM) receptors. Several agents (e.g. …

Varenicline (sold under the brand name Chantix), Jani explained, is a nicotinic receptor partial agonist. That’s a concise …

Nicotinic antagonists. Nicotinic antagonists fall into two distinct groups: ganglion blockers and peripheral muscle relaxants. The differences between the nicotinic receptors at autonomic ganglia and those at the neuromuscular junction mentioned above form the basis of the distinct pharmacodynamic actions of these two classes of drugs.

A nicotinic antagonist is a type of anticholinergic drug that inhibits the action of acetylcholine (ACh) at nicotinic acetylcholine receptors. These compounds are …

Nicotinic antagonists. The differences between the nicotinic receptors at autonomic ganglia and those at the neuromuscular junction mentioned above form the basis of the distinct pharmacodynamic actions of these two classes of drugs. Generally, ganglion blockers have little or no effect on transmission at the neuromuscular junction.

Nicotine disrupts the normal relationship between a neurotransmitter (chemical communicator) called acetylcholine (ACh) and …

Adv Pharmacol. 2014;69:513-51. doi: 10.1016/B978-0-12-420118-7.00013-5. Nicotinic receptor antagonists as treatments for nicotine abuse. Crooks PA(1) …

Nicotine is one of the most addictive substances known to science and binds to specialized receptors that already exist in …

Nicotinic antagonists discriminate between the ganglionic (neuronal, NN) and the neuromuscular nicotinic AChR (NM) receptors. Several agents (e.g. …

Varenicline and cytisine are partial agonists at the α4β2* nicotinic acetylcholine receptor (nAChR). Bupropion is an antidepressant but is also an antagonist at …

He began vaping tetrahydrocannabinol, or THC, a chemical in marijuana known for its effect on dopamine receptors in the …

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Midbrain dopaminergic (DA) neurons are governed by an endogenous cholinergic system, originated in the mesopontine nuclei.

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Drugs that bind to nicotinic cholinergic receptors (RECEPTORS, NICOTINIC) and block the actions of acetylcholine or cholinergic agonists. Nicotinic antagonists …