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A type of mutation in which the altered gene product lacks the molecular function of the wild-type gene. Synonyms: Amorphic Mutation, Null Mutation. See also:.

Dendritic spines are postsynaptic domains that shape structural and functional properties of neurons. Upon neuronal activity, …

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Exposure to iodine in the neonatal intensive care unit (NICU) may increase a baby’s risk for loss of thyroid function, a new study suggests.

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Loss-of-function mutation: A mutation that results in reduced or abolished protein function. Gain-of-function mutations,which are much less common, confer an …